Advances in Laboratory Techniques for Diagnosing Diabetes Mellitus

  • Wedad Qubayl Alruwaytie et al.
Keywords: Diabetes mellitus, laboratory techniques, continuous glucose monitoring (CGM), fasting blood glucose, A1C measurements, biomarkers, C-peptide, insulin assays, point-of-care testing (POCT), molecular diagnostics, genetic testing, next-generation sequencing, monogenic diabetes, digital health innovations, patient empowerment.

Abstract

Recent advances in laboratory techniques for diagnosing diabetes mellitus have significantly improved both the accuracy and efficiency of detection. Traditional methods, such as fasting blood glucose tests and A1C measurements, have been enhanced with the introduction of continuous glucose monitoring (CGM) systems. These devices provide real-time glucose readings, allowing for more dynamic management of blood sugar levels. Additionally, the use of specific biomarkers, such as C-peptide and insulin assays, has become more prevalent, helping to distinguish between type 1 and type 2 diabetes. Emerging technologies like point-of-care testing (POCT) facilitate quicker diagnosis in clinical settings, enabling timely intervention and personalized treatment plans for patients. Moreover, advancements in molecular diagnostics, including genetic testing and next-generation sequencing, are shedding light on the hereditary factors of diabetes mellitus. These techniques allow for the identification of gene mutations associated with monogenic forms of diabetes, such as Maturity Onset Diabetes of the Young (MODY). Such insights can tailor prevention strategies and therapies based on individual risk profiles. Coupled with digital health innovations, like mobile apps that track glucose levels and dietary habits, these laboratory advancements empower patients to take a proactive role in their diabetes management, fostering better health outcomes and quality of life.

Author Biography

Wedad Qubayl Alruwaytie et al.

Wedad Qubayl Alruwaytie¹, Nouf Naji Al Khateeb², Wafa Dawas D. Alruwaili³, Hamdah Menwer Mualla Almarashi⁴, Fatimah Ali Mohammed Alsharif⁵, Azizah Theyab Almurashi⁶, Ala Abdulla M. Alenezi⁷, Nuh Sayfi Almutairi⁸, Fayez Mushafiq H. Alazmi⁹, Aljohani Nada Abdulaziz S.¹⁰

¹ Senior specialist Laboratory, Ministry of Health - Madinah Health Cluster - Al-Miqat General Hospital, Madinah, Saudi Arabia
² Senior technologist, Ad Diriyah Hospital, Riyadh, Riyadh Region, Saudi Arabia
³ Laboratories and Medical Technology, Maternity and Children’s Hospital, Sakaka, Al-Jouf, Saudi Arabia
⁴ Laboratory Technician, Ministry of Health - Madinah Health Cluster - Al-Miqat General Hospital, Madinah, Saudi Arabia
⁵ Laboratory Technician, Ministry of Health - Madinah Health Cluster - Al-Miqat General Hospital, Madinah, Saudi Arabia
⁶ Laboratory Technician, Ministry of Health - Madinah Health Cluster - Al-Miqat General Hospital, Madinah, Saudi Arabia
⁷ Laboratory Specialist, Regional Laboratory and Blood Bank, Arar, Northern Borders, Saudi Arabia
⁸ Laboratory Technician, Ministry of Health - Madinah Health Cluster - Al-Miqat General Hospital, Madinah, Saudi Arabia
⁹ Laboratory Specialist, Al-Qurayyat General Hospital, Al-Qurayyat, Al-Jouf, Saudi Arabia
¹⁰ Specialist-Laboratory - Molecular Genetics, Ministry of Health - Madinah Health Cluster - Al-Miqat General Hospital, Madinah, Saudi Arabia

Published
2023-02-04
Section
Regular Issue