Regenerative Endodontic Treatment- Overview

Abstract

Introduction: Endodontic Therapy saves millions of teeth each year. Modern treatment modalities offers high level of success, but an ideal treatment might compromise of regenerative approaches in which diseased or necrotic pulp tissues are replaced with healthy pulp. Regenerative endodontics is based on the concept of tissue engineering and attempts to restore the root canals of teeth to their healthy state to encourage continued development of the root and surrounding tissues. Concepts from the fields of pulp biology, dental trauma, and tissue engineering are applied in this biologically based treatment modality as attempts are made to promote continued root development, apical closure and increased thickness in dentinal wall in permanent teeth with necrotic pulps and immature apices. These developments have a promising impact on the efforts to retain natural teeth, the primary goal of endodontic treatments.

Aim of Work: this review provides an overview of regenerative endodontics, the clinical considerations for regeneration therapy and as an assessment of the expected outcome.

Methodology: This article is a comprehensive review of PUBMED from the year 2001 to 2017.

Conclusion: Revascularization/revitalization procedures performed according to the current clinical protocols have been able to achieve clinically and radiographically successful outcomes for immature necrotic permanent teeth. However, repair rather than true regeneration is achieved with the current protocols, and it is hoped that new research in the field of stem cell-based pulp engineering will pave the way for true pulp dentin regeneration and improve the treatment outcomes.