A Comparative Study of Anaesthetic Efficacy of 0.5% Hyperbaric Levobupivacaine Vs 0.5% Hyperbaric Bupivacaine for Intrathecal Anaesthesia in Below Umbilical Surgeries - A Prospective Randomized Study
Abstract
Background: Spinal anesthesia is a common technique for below umbilical surgeries, with the choice of local anesthetic playing a crucial role in patient outcomes. This study aimed to compare the anesthetic efficacy and safety of 0.5% hyperbaric Bupivacaine and 0.5% hyperbaric Levobupivacaine for spinal anesthesia in below umbilical surgeries.
Methodology: A prospective randomized study was conducted among patients undergoing elective infraumbilical surgeries under spinal anesthesia at Sri Manakula Vinayagar Medical College Hospital were included. They were randomly assigned to receive either 0.5% hyperbaric Bupivacaine or 0.5% hyperbaric Levobupivacaine intrathecally.
Results: The level of sensory blockade was comparable between the Bupivacaine and Levobupivacaine groups (P = 0.360), indicating similar efficacy in achieving sensory anesthesia. The mean onset time for motor blockade was significantly quicker in the Bupivacaine group (3.46 min) compared to the Levobupivacaine group (9.28 min), with a statistically significant difference (P = 0.001). Similarly, the mean duration of motor blockade was longer in the Bupivacaine group (201.40 min) compared to the Levobupivacaine group (181.28 min), with a significant difference (P = 0.001). There were no significant differences in heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure, or oxygen saturation between the Bupivacaine and Levobupivacaine groups at various time intervals throughout the study period.
Conclusion: Both 0.5% hyperbaric Bupivacaine and 0.5% hyperbaric Levobupivacaine demonstrated comparable efficacy and safety profiles for spinal anesthesia in below umbilical surgeries.
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